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Other properly examined nAChR genes involve the CHRNA4 and CHRNB2, which have been linked as Autosomal Dominant Nocturnal Frontal Lobe Epilepsy (ADNFLE) genes.[42][46] Both of those of such nAChR subunits are current within the brain and the incidence of mutations in these two subunits result in a generalized type of epilepsy. Examples contain the